Evaluating products.
How do I choose safe adjunctive products for migraine?
Shelf order follows the evidence ladder: magnesium leads (guideline Level B, multiple RCTs — with its dose conversation built into the tag), riboflavin is the honest penny-a-day second (adult trials, 3-month commitment), and CoQ10 closes on one small trial, graded accordingly. All three are adjuncts to the medical spine — acute therapy, indicated prevention, and the regularity protocol. The products below are educational examples — not medical recommendations.
Thorne Magnesium Bisglycinate
by Thorne · Prevention Mineral
Score
Magnesium carries the strongest supplement evidence in migraine prevention — trials at ~600 mg/day elemental reduced attack frequency, and guidelines list it as a Level B preventive. 🚨 The studied 600 mg/day exceeds the 350 mg/day over-the-counter upper limit — reaching it is a physician-conversation dose, not a self-prescription. Glycinate is gentler on the gut than the oxide/citrate used in trials; the trade-off is capsule math (3 caps). High doses cause loose stools — back off if it happens.
Runner-ups
NOW Riboflavin 400 mg
by NOW Foods · Mitochondrial Energy (B2)
Qunol Ultra CoQ10 (100 mg)
by Qunol · Mitochondrial Cofactor