Compare the three ashwagandha formats head-to-head — the trial-material extract, the alternative licensed extract, and the traditional-format option. In ashwagandha's comparison, the honest principle is: the extract IS the product, and the physician's thyroid sign-off IS the purchase prerequisite.



| Metric | 🏆KSM-66 Ashwagandha 600 mg KSM-66 (various licensees) | Sensoril Ashwagandha 250 mg Sensoril (various licensees) | Himalaya Organic Ashwagandha Himalaya |
|---|---|---|---|
| Delivery Form | Capsule | Capsule | Caplet |
| Strength | 600 mg (5% withanolides) | 250 mg (10% withanolides) | 670 mg (root powder, unstandardized) |
| Servings / Container | 60 | 60 | 60 |
| Retail Price | $19.99 | $16.99 | $15.99 |
| Cost / Serving | $0.33 | $0.28 | $0.27BEST 💰 |
| Overall Score | NaN/100 | NaN/100 | NaN/100 |
| 3rd-Party Testing | None | None | None |
| Vegan Friendly | ✓ Yes | ✓ Yes | ✓ Yes |
KSM-66 (root-only, 5%) or Sensoril (root+leaf, 10%) — the named, standardized extracts with the trial bases. Unnamed 'ashwagandha root powder' is the tradition's reputation without the molecule's pharmacology.
The GAD and thyroid trials both used 600 mg KSM-66 daily — the dose the evidence owns. The 300 mg 'gentle' products and the 1,000+ mg 'maximum' products bracket the studied range without trial support at their own numbers.
The molecule stimulates thyroid output — case reports of thyrotoxicosis exist, and the Graves'/over-replacement population is on the wrong side of a directional pharmacology. The physician conversation is non-negotiable.
The most replicated finding: ~20–30% serum cortisol reduction across trials — the stress-resilience claim's evidence base, honestly sized.
Contraindicated in pregnancy — the traditional contraindication with pharmacological support. One of the category's few absolute exclusions.
Additive with benzodiazepines, sleep aids, and alcohol — the GABAergic pharmacology stacking with pharmaceutical sedation. No unsupervised combination.