Product Comparison
Compare the three formats head-to-head — the single-strain flagship (LGG), the IBS indication's own strain (35624 at its studied 1 billion dose), and the medical-grade De Simone multi-strain (pouchitis-tier, refrigerated). In probiotics' comparison, the honest principle is the page's whole lesson: the strain is the product, the dose is the strain's studied dose, and the unnamed blend is the category's empty default.
At a glance
Culturelle Digestive Health (L. rhamnosus GG)
Align Daily (B. longum 35624)
Visbiome (De Simone Formulation, 8 Strains)
Multi-dimensional comparison
Multi-dimensional Comparison
| Metric | 🏆Culturelle Digestive Health (L. rhamnosus GG) Culturelle | Align Daily (B. longum 35624) Align | Visbiome (De Simone Formulation, 8 Strains) Visbiome (ExeGi Pharma) |
|---|---|---|---|
| Delivery Form | Capsule | Capsule | Powder Packet |
| Strength | 10 billion CFU (Lactobacillus rhamnosus GG) | 1 billion CFU (Bifidobacterium longum 35624, now labeled 3565) | 112.5 billion CFU, 8 strains (the De Simone Formulation) |
| Servings / Container | 30 | 28 | 60 |
| Retail Price | $24.99 | $29.99 | $64.99 |
| Cost / Serving | $0.83BEST 💰 | $1.07 | $1.08 |
| Overall Score | 79/100 | 76/100 | 76/100 |
| 3rd-Party Testing | None | None | None |
| Vegan Friendly | — No | — No | — No |
Did you know?
The strain names ARE the products
Full strain designations on the label or the bottle borrows what it doesn't carry: the category's entire evidence lives in named organisms — L. rhamnosus GG, B. longum 35624, GR-1/RC-14, the De Simone 8 — and every unnamed 'blend' is the borrowing rule in a bottle.
The dose is the indication
Three studied doses spanning two orders of magnitude on this one page: 1 billion for the IBS strain, 10 billion for LGG, 112.5 billion for the pouchitis formulation. 'More CFU' is a label contest; the studied dose is pharmacology.
Visitors, not residents
Most strains pass through in days — the benefit happens during transit, daily dosing sustains it, and stopping stops it. The Weizmann personalization data adds the honesty: even the transit varies person to person.
Storage is part of the dose
Refrigerated products (the De Simone tier) need the cold chain; shelf-stable ones are engineered for the cabinet — both legitimate, follow the label. The guarantee that matters: CFU at EXPIRATION, not at manufacture.
The prebiotic foundation
The fiber pattern feeds the residents; the probiotic visits them — the plate's full strategy is both, and no capsule replaces the foundation our gut pages build.
The kitchen-sink category
Ten-plus strains at token doses, no combination evidence, no names that trace to trials — the format whose label length substitutes for any single studied organism. This page's retirement.